⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23142757 | 0.92 | — | — | |
| SCHEMBL669588 | 0.83 | — | — | |
| SCHEMBL14380693 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL1500025 | 0.79 | — | — | |
| SCHEMBL16573352 | 0.77 | KDM4E (0.38) | — | |
| SCHEMBL18773605 | 0.75 | DPP4 (0.31) | — | |
| SCHEMBL17881651 | 0.75 | — | — | |
| SCHEMBL15080518 | 0.73 | CYP19A1 (0.31) | — | |
| SCHEMBL25754678 | 0.73 | CYP19A1 (0.31) | — | |
| SCHEMBL24246546 | 0.73 | CYP19A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115390-B1 | HYDROXAMATE-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON INC (US) | 2009-07-22 | — | — | EP | disclosed |
| US-7060683-B2 | Hydroxamate-containing cysteine and serine protease inhibitors | CEPHALON, INC. (US) | 2006-06-13 | — | — | US | disclosed |
| EP-1115390-A4 | HYDROXAMATE-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON INC (US) | 2004-08-11 | — | — | EP | disclosed |
| US-20040106558-A1 | Hydroxamate-containing cysteine and serine protease inhibitors | CEPHALON, INC. | 2004-06-03 | — | — | US | disclosed |
| US-6686335-B1 | INHIBITING CALPAIN | CEPHALON, INC. | 2004-02-03 | — | — | US | disclosed |
| EP-1115390-A1 | HYDROXAMATE-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000016767-A1 | HYDROXAMATE-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 2000-03-30 | — | — | WO | disclosed |