Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.50 |
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969040 | 0.93 | CNR2 (0.61) | CNR2CNR1GAA | |
| SCHEMBL1464787 | 0.89 | CNR2 (0.55) | CNR2CNR1NPY5RL3MBTL1SCN9A | |
| SCHEMBL1464022 | 0.87 | CNR2 (0.64) | CNR2MAPK14LMNAMAPK13 | |
| SCHEMBL3963516 | 0.84 | CNR2 (0.52) | CNR2CNR1NPY5RL3MBTL1MAPK14 | |
| SCHEMBL3964403 | 0.83 | CNR2 (0.51) | CNR2CNR1NPY5RL3MBTL1MAPK14 | |
| SCHEMBL3967896 | 0.81 | CNR2 (0.53) | CNR2CNR1MAPK14GAALMNA | |
| SCHEMBL1464553 | 0.80 | CNR2 (0.56) | CNR2CNR1NPY5RGAA | |
| SCHEMBL3968663 | 0.79 | CNR2 (0.53) | CNR2CNR1L3MBTL1SCN9ALMNA | |
| SCHEMBL1465446 | 0.79 | CNR2 (0.64) | CNR2MAPK14LMNAMAPK13 | |
| SCHEMBL1464325 | 0.79 | CNR2 (0.54) | CNR2CNR1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |