Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.55 |
| ▸ | CNR1 | P21554 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963697 | 0.95 | CNR2 (0.54) | CNR2CNR1GAAPTK2BRAF1 | |
| SCHEMBL1464294 | 0.90 | CNR2 (0.66) | CNR2CNR1GAARAF1FLT3 | |
| SCHEMBL1465096 | 0.90 | CNR2 (0.66) | CNR2PTK2BRAF1LMNAMAPK14 | |
| SCHEMBL3962815 | 0.85 | CNR2 (0.45) | CNR2CNR1GAAFLT3ALDH1A1 | |
| SCHEMBL3967896 | 0.78 | CNR2 (0.53) | CNR2CNR1GAAFLT3ALDH1A1 | |
| SCHEMBL1464890 | 0.77 | CNR2 (0.70) | CNR2CNR1GAAFLT3ALDH1A1 | |
| SCHEMBL1463633 | 0.76 | CNR2 (0.76) | CNR2CNR1GAASMN1; SMN2MAPK14 | |
| SCHEMBL1464646 | 0.76 | CNR2 (0.76) | CNR2CNR1GAAFLT3ALDH1A1 | |
| SCHEMBL1465890 | 0.76 | CNR2 (0.76) | CNR2CNR1LMNAMAPK14MAPK13 | |
| SCHEMBL1463758 | 0.76 | CNR2 (0.69) | CNR2CNR1ALDH1A1LMNAMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |