SCHEMBL3963624

SCHEMBL3963624

COC(=O)COC(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL129132 0.78 MGAM (0.52)
SCHEMBL343805 0.77 GAA (0.52)
SCHEMBL12914666 0.77 TSHR (0.43)
SCHEMBL10010655 0.76 TSHR (0.48)
SCHEMBL15949790 0.76 TSHR (0.63)
SCHEMBL2607864 0.76
SCHEMBL4443115 0.76
SCHEMBL4443116 0.76
SCHEMBL22667219 0.76 MGAM (0.50)
SCHEMBL28443659 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5187306-A Reacting unsaturated amides with metallic bases to form metal salts, which are reacted with halogenated formic acid esters NIPPON PAINT CO., LTD. (JP) 1993-02-16 US claimed
CN-118139868-A Orally bioavailable nucleoside analogs 维纳拓尔斯制药公司 2024-06-04 CN disclosed
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2023-10-05 US disclosed
US-11530189-B2 Carbamate compounds and methods of making and using same H. LUNDBECKA/S (DK) 2022-12-20 US disclosed
WO-2022247760-A1 HETEROCYCLIC COMPOUNDS AS KRAS INHIBITOR, AND PREPARATION THEREFOR AND USE THEREOF IN TREATMENT 上海科州药物研发有限公司 2022-12-01 WO disclosed
WO-2022228318-A1 INDOLINE-CONTAINING SPIRO DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE 长春金赛药业有限责任公司 2022-11-03 WO disclosed
US-20210188793-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME LUNDBECK LA JOLLA RESEARCH CENTER, INC. 2021-06-24 US disclosed
US-11021453-B2 Carbamate compounds and methods of making and using same LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) 2021-06-01 US disclosed
US-20200270223-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2020-08-27 US disclosed
EP-3698782-A1 CARBAMATE COMPOUNDS FOR USE IN THERAPY Lundbeck La Jolla Research Center, Inc. (US) 2020-08-26 EP disclosed
US-20080085923-A1 Thrombin Receptor Antagonists Based On The Modified Tricyclic Unit Of Himbacine SCHERING CORPORATION 2008-04-10 US disclosed
EP-0882048-B1 3-ALKYLIMIDAZOPYRIDINES ALTANA PHARMA AG (DE) 2005-05-04 EP disclosed
US-6096758-A 3-METHYLIMIDAZOPYRIDINES USED FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2000-08-01 US disclosed
EP-0882048-A1 3-METHYLIMIDAZOPYRIDINES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1998-12-09 EP disclosed
WO-1997027193-A1 IMIDAZOPYRIDINE HALIDES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1997-07-31 WO disclosed
WO-1997027192-A1 3-METHYLIMIDAZOPYRIDINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1997-07-31 WO disclosed
US-5434296-A Reacting carbamate with metallic base to form salt; reacting with unsaturated acid halide to acylate NIPPON PAINT CO., LTD. (JP) 1995-07-18 US disclosed
EP-0465162-B1 Process for producing unsaturated carbamic acid esters NIPPON PAINT CO LTD (JP) 1994-12-07 EP disclosed
US-5187306-A Reacting unsaturated amides with metallic bases to form metal salts, which are reacted with halogenated formic acid esters NIPPON PAINT CO., LTD. (JP) 1993-02-16 US disclosed
EP-0465162-A1 Process for producing unsaturated carbamic acid esters NIPPON PAINT CO., LTD. (JP) 1992-01-08 EP disclosed