Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838259 | 0.90 | TSHR (0.50) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL4316171 | 0.90 | TSHR (0.50) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL9623718 | 0.88 | TSHR (0.48) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL9622726 | 0.88 | TSHR (0.48) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL9623303 | 0.88 | TSHR (0.48) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL9623579 | 0.88 | TSHR (0.48) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL9623306 | 0.88 | TSHR (0.48) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL9623317 | 0.88 | TSHR (0.48) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL9623485 | 0.88 | TSHR (0.48) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL3001397 | 0.86 | TSHR (0.57) | GABRA1GABRB2TSHRPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601784-B2 | 1,1,2,2-tetrakis(4-hydroxyphenyl)ethane is used to molecular alignment, chemical stabilization, heat resist, flexiable and modification of the polyether having hydrogen bond sites; for waste water treatments, energy transducers, conductors | NIPPON SODA CO., LTD. (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20050228167-A1 | Molecular compounds containing polymers having hydrogen bond sites as the constituent compounds | NIPPON SODA CO., LTD. (JP) | 2005-10-13 | — | — | US | disclosed |
| EP-0304125-B1 | Heat-hardenable compositions based on polyglycidyl ethers and polyhydric phenols, halogenated tetraphenols, polyglycidyl ethers and process for preparing tetraphenols | SHELL INT RESEARCH (NL) | 1994-03-23 | — | — | EP | disclosed |
| EP-0533202-A1 | Use of capped surfactants for production of rigid polyurethane foams blown with hydrochlorofluorocarbons | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| EP-0344165-A1 | THERMOSET POLYMERS OF STYRENE TERMINATED TETRAKIS PHENOLS. | ALLIED CORP (US) | 1989-12-06 | — | — | EP | disclosed |
| EP-0084966-B1 | AQUEOUS COMPOSITIONS CONTAINING OVERBASED MATERIALS | The Lubrizol Corporation (US) | 1989-11-08 | — | — | EP | disclosed |
| EP-0304125-A2 | Heat-hardenable compositions based on polyglycidyl ethers and polyhydric phenols, halogenated tetraphenols, polyglycidyl ethers and process for preparing tetraphenols | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-02-22 | — | — | EP | disclosed |
| US-4786700-A | PREPARED FROM STYRENE TERMINATED TETRAKISPHENOLS, CIRCUIT BOARDS | ALLIED-SIGNAL, INC. (US) | 1988-11-22 | — | — | US | disclosed |
| WO-1988005059-A1 | THERMOSET POLYMERS OF STYRENE TERMINATED TETRAKIS PHENOLS | ALLIED CORPORATION (US) | 1988-07-14 | — | — | WO | disclosed |
| US-4728708-A | Thermoset polymers of styrene terminated tetrakis phenols | ALLIED CORPORATION (US) | 1988-03-01 | — | — | US | disclosed |
| US-4258137-A | INCORPORATING AN EPOXY RESIN AND CURING AGENT TO ATTAIN RIGIDITY | W. R. GRACE & CO. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4250005-A | Radiation cross-linked polyurethane foams | SCOTT PAPER COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| US-4243759-A | POLYURETHANE FOAMS | MOBAY CHEMICAL CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
| US-4229376-A | Polycyclic polyamines | HENKEL CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4221877-A | Modified diphenylmethane diisocyanates useful in polyurethanes or polyisocyanurates | TEXACO DEVELOPMENT CORP. (US) | 1980-09-09 | — | — | US | disclosed |
| US-4209609-A | INTERMEDIATES FOR POLYURETHANE FOAMS OF LOW FRIABILITY AND GOOD DIMENSIONAL STABILITY | MOBAY CHEMICAL CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| US-4148950-A | CURING AGENTS | AMERON, INC. (US) | 1979-04-10 | — | — | US | disclosed |
| US-4144027-A | SHRINKPROOFING KERATIN-CONTAINING FABRICS BY REACTION WITH A POLYETHER POLYOL AND A DIISOCYANATE | MILLIKEN RESEARCH CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-4115300-A | DIEPOXIDES | THE UPJOHN COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4046744-A | Thermosetting coatings based on ketoxime-blocked isocyanates and oxazolidines | ROHM AND HAAS COMPANY (US) | 1977-09-06 | — | — | US | disclosed |