Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455711 | 0.92 | ADORA1 (0.46) | ADORA1ADORA2BADORA2AHTTMAPT | |
| SCHEMBL14318538 | 0.87 | ADORA1 (0.43) | ADORA1ADORA2BADORA2AHTTMAPT | |
| SCHEMBL2453587 | 0.85 | DHODH (0.46) | ADORA1ADORA2BHTTMAPTALDH1A1 | |
| SCHEMBL2458090 | 0.82 | MEN1 (0.47) | ADORA1ADORA2AMAPTALDH1A1MEN1 | |
| SCHEMBL7868431 | 0.82 | MAPT (0.44) | HTTMAPTMAP2K1ALDH1A1TSHR | |
| SCHEMBL4355262 | 0.80 | HSD17B10 (0.55) | HTTMAPTRECQLCXCR2ALDH1A1 | |
| SCHEMBL3793311 | 0.79 | HSD17B10 (0.41) | HTTMAPTCXCR2ALDH1A1HSD17B10 | |
| SCHEMBL7712954 | 0.79 | DHODH (0.41) | ADORA1ADORA2BADORA2AMAPTMAP2K1 | |
| SCHEMBL7868425 | 0.79 | MEN1 (0.47) | ADORA1ADORA2BADORA2AHTTRECQL | |
| SCHEMBL7873475 | 0.79 | ADORA1 (0.38) | ADORA1ADORA2BADORA2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11292835-A | — | — | None | — | — | JP | disclosed |
| US-8937072-B2 | Substituted cyanoaniline compounds, preparation and use thereof | SINOCHEM CORPORATION (CN) | 2015-01-20 | — | — | US | disclosed |
| US-20140213598-A1 | SUBSTITUTED CYANOANILINE COMPOUNDS, PREPARATION AND USE THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2014-07-31 | — | — | US | disclosed |
| WO-2012171484-A1 | SUBSTITUTED CYANOANILINE COMPOUNDS, PREPARATION AND USE THEREOF | 中国中化股份有限公司 (CN) | 2012-12-20 | — | — | WO | disclosed |
| US-7473777-B2 | Method for production of halogen-containing phthalocyanine compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2009-01-06 | — | — | US | disclosed |
| US-20050203293-A1 | Method for production of halogen-containing phthalocyanine compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2005-09-15 | — | — | US | disclosed |
| EP-0882768-B1 | Method for producing of phthalocyanine compound | NIPPON CATALYTIC CHEM IND (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-6034236-A | REACTING A PHTHALONITRILE WITH A METAL OXIDE IN PRESENCE OF A SULFONIC ACID CATALYST | NIPPON SHOKUBAI CO., LTD. (JP) | 2000-03-07 | — | — | US | disclosed |
| JP-H11292835-A | PRODUCTION OF AMINO-SUBSTITUTED PHTHALONITRILE COMPOUND | NIPPON SHOKUBAI CO LTD | 1999-10-26 | — | — | JP | disclosed |
| EP-0523959-B1 | Novel phthalocyanine compounds, production method thereof, and near infrared ray absorption materials containing the same | NIPPON CATALYTIC CHEM IND (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0882768-A2 | Method for producing of phthalocyanine compound | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5359056-A | Lightfastness, solvent solubility | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0523959-A2 | Novel phthalocyanine compounds, production method thereof, and near infrared ray absorption materials containing the same | NIPPON SHOKUBAI CO., LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213598-A1 | SUBSTITUTED CYANOANILINE COMPOUNDS, PREPARATION AND USE THEREOF | CROCC, MASTL, SLC7A1 | ADORA1 1712/4885ADORA2B 4072/4885ADORA2A 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.