Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 19/20 | 0.74 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.74 |
| ▸ | KIT | P10721 | 1/20 | 0.74 |
| ▸ | AXL | P30530 | 1/20 | 0.74 |
| ▸ | FLT3 | P36888 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970086 | 0.92 | CSF1R (0.75) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3964211 | 0.90 | CSF1R (0.73) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL13405731 | 0.85 | CSF1R (1.00) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL31157969 | 0.85 | CSF1R (1.00) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3970216 | 0.83 | CSF1R (0.58) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3970327 | 0.82 | CSF1R (0.51) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3964156 | 0.80 | CSF1R (0.75) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3963254 | 0.78 | CSF1R (0.49) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3966702 | 0.78 | CSF1R (0.51) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3970081 | 0.78 | CSF1R (0.48) | CSF1RNTRK1KITAXLFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807407-B1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-29 | — | — | EP | claimed |