Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3959608 | 0.95 | PTGER4 (0.61) | PTGER4 | |
| SCHEMBL3534260 | 0.83 | PTGER4 (0.63) | PTGER4 | |
| SCHEMBL3536863 | 0.81 | PTGER4 (0.65) | PTGER4 | |
| SCHEMBL3537522 | 0.81 | PTGER4 (0.65) | PTGER4 | |
| SCHEMBL3540622 | 0.81 | PTGER4 (0.68) | PTGER4 | |
| SCHEMBL3532607 | 0.79 | PTGER4 (0.60) | PTGER4 | |
| SCHEMBL4691018 | 0.77 | PTGER4 (0.61) | PTGER4 | |
| SCHEMBL4691076 | 0.77 | PTGER4 (0.55) | PTGER4 | |
| SCHEMBL4690885 | 0.77 | PTGER4 (0.62) | PTGER4 | |
| SCHEMBL1756460 | 0.76 | PTGER4 (1.00) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528157-B2 | EP4 receptor antagonists | ASTERAND UK LIMITED (GB) | 2009-05-05 | — | — | US | disclosed |
| US-20070123575-A1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK ACQUISITION LIMITED (GB) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123575-A1 | EP4 RECEPTOR ANTAGONISTS | PTGER4, NR4A1, PTGER1 | PTGER4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.