Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | ESR1 | P03372 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | ATM | Q13315 | 2/20 | 0.69 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | ACHE | P22303 | 2/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.64 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.64 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17387170 | 0.87 | CACNA1H (0.78) | CACNA1HKMT2AESR1MAPTATM | |
| SCHEMBL571508 | 0.85 | ESR1 (0.76) | CACNA1HKMT2AESR1MAPTCACNA1G | |
| SCHEMBL22465736 | 0.84 | CACNA1H (1.00) | CACNA1HKMT2AESR1MAPTATM | |
| SCHEMBL31517131 | 0.83 | MAPT (0.65) | CACNA1HKMT2AESR1MAPTATM | |
| SCHEMBL22465610 | 0.82 | CACNA1H (0.81) | CACNA1HKMT2AESR1MAPTATM | |
| SCHEMBL29394512 | 0.82 | CACNA1H (1.00) | CACNA1HKMT2AESR1MAPTATM | |
| SCHEMBL145714 | 0.82 | CACNA1H (1.00) | CACNA1HKMT2AESR1MAPTATM | |
| SCHEMBL145713 | 0.82 | CACNA1H (1.00) | CACNA1HKMT2AESR1MAPTATM | |
| SCHEMBL17387051 | 0.81 | CACNA1H (0.77) | CACNA1HKMT2AESR1MAPTATM | |
| SCHEMBL22465618 | 0.81 | CACNA1H (1.00) | CACNA1HKMT2AESR1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9011902-B2 | Composition for vaginal use | POLICHEM SA (LU) | 2015-04-21 | — | — | US | disclosed |
| EP-1978981-B1 | COMPOSITIONS FOR VAGINAL USE | POLICHEM SA (LU) | 2009-07-22 | — | — | EP | disclosed |
| US-20090035361-A1 | Composition for vaginal use | POLICHEM S.A. (LU) | 2009-02-05 | — | — | US | disclosed |
| EP-1978981-A1 | COMPOSITIONS FOR VAGINAL USE | Polichem S.A. (LU) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007085327-A1 | COMPOSITIONS FOR VAGINAL USE | POLICHEM S.A. (LU) | 2007-08-02 | — | — | WO | disclosed |