Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966055 | 1.00 | GRIK1 (0.38) | GRIK1GRIK2SLC22A6HDAC2SMN1; SMN2 | |
| SCHEMBL22500687 | 0.83 | GRIK1 (0.40) | GRIK1GRIK2SLC22A6HDAC2SMN1; SMN2 | |
| SCHEMBL22500689 | 0.83 | GRIK1 (0.40) | GRIK1GRIK2SLC22A6HDAC2SMN1; SMN2 | |
| SCHEMBL14852861 | 0.82 | GRIK1 (0.37) | GRIK1GRIK2MAPT | |
| SCHEMBL15909791 | 0.82 | GRIK1 (0.37) | GRIK1GRIK2MAPT | |
| SCHEMBL17920045 | 0.82 | GRIK1 (0.37) | GRIK1GRIK2MAPT | |
| SCHEMBL1709871 | 0.82 | GRIK1 (0.37) | GRIK1GRIK2MAPT | |
| SCHEMBL13540707 | 0.82 | GRIK1 (0.37) | GRIK1GRIK2MAPT | |
| SCHEMBL17526444 | 0.79 | GRIK1 (0.32) | GRIK1GRIK2LMNA | |
| SCHEMBL473722 | 0.78 | SLC22A6 (0.37) | GRIK1GRIK2SLC22A6SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090175981-A1 | COMPOSITIONS, METHODS AND USES FOR A NOVEL FAMILY OF PEPTIDES | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2009-07-09 | — | — | US | disclosed |
| US-7498404-B2 | Compositions, methods and uses for a novel family of peptides | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2009-03-03 | — | — | US | disclosed |
| EP-1765374-A2 | COMPOSITIONS, METHODS AND USES FOR A NOVEL FAMILY OF PEPTIDES | The Texas A & M Univsersity System (US) | 2007-03-28 | — | — | EP | disclosed |
| US-20060228398-A1 | Compositions, methods and uses for a novel family of peptides | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2006-10-12 | — | — | US | disclosed |
| WO-2005074626-A2 | COMPOSITIONS, METHODS AND USES FOR A NOVEL FAMILY OF PEPTIDES | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2005-08-18 | — | — | WO | disclosed |