⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5407310 | 1.00 | — | — | |
| SCHEMBL10374846 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL11406903 | 0.97 | — | — | |
| SCHEMBL1648618 | 0.96 | — | — | |
| SCHEMBL5403195 | 0.96 | — | — | |
| Iodide SCHEMBL18249294 | 0.93 | — | — | |
| SCHEMBL6187126 | 0.71 | — | — | |
| SCHEMBL10332690 | 0.71 | — | — | |
| SCHEMBL11165550 | 0.71 | — | — | |
| SCHEMBL2254566 | 0.69 | CA1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019202459-A1 | USE OF 4-SUBSTITUTED PHENYLAMIDINE COMPOUNDS FOR CONTROLLING DISEASE RUST DISEASES IN PLANTS | PI INDUSTRIES LTD. (IN) | 2019-10-24 | — | — | WO | claimed |
| EP-1504014-B1 | PROCESS FOR PREPARATION OF CYCLIC PRODRUGS OF PMEA AND PMPA | METABASIS THERAPEUTICS INC (US) | 2015-12-02 | — | — | EP | claimed |
| US-7553850-B2 | Tricyclic-bridged piperidinylidene derivatives as δ-opioid modulators | JANSSEN PHARMACEUTICA NV (BG) | 2009-06-30 | — | — | US | claimed |
| EP-1910353-A1 | TRICYCLIC DELTA- OPIOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-16 | — | — | EP | claimed |
| US-20070203339-A1 | Process for Preparation of Cyclic Prodrugs of PMEA and PMPA | METABASIS THERAPEUTICS, INC. | 2007-08-30 | — | — | US | claimed |
| US-7193081-B2 | 9-(2-(2,4-cis(S)-4-(3-chlorophenyl)-2-oxo-1,3,2-dioxaphosphor-inan-2 -yl)methoxyethyl)adenine by coupling the dichloridate of 9-(2-phosphonyl- methoxyethyl- or propyl)adenine (PMEA)(PMPA) with a 1-(chlorophenyl) propylene-1,3-diol | METABASIS THERAPEUTICS, INC. (US) | 2007-03-20 | — | — | US | claimed |
| WO-2007030089-A1 | TRICYCLIC DELTA- OPIOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-03-15 | — | — | WO | claimed |
| EP-1504014-A4 | PROCESS FOR PREPARATION OF CYCLIC PRODRUGS OF PMEA AND PMPA | METABASIS THERAPEUTICS INC (US) | 2006-06-07 | — | — | EP | claimed |
| US-20060030585-A1 | Tricyclic delta-opioid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-02-09 | — | — | US | claimed |
| EP-1504014-A2 | PROCESS FOR PREPARATION OF CYCLIC PRODRUGS OF PMEA AND PMPA | Metabasis Therapeutics, Inc. (US) | 2005-02-09 | — | — | EP | claimed |
| US-20030225277-A1 | Process for preparation of cyclic prodrugs of PMEA and PMPA | METABASIS THERAPEUTICS, INC. | 2003-12-04 | — | — | US | claimed |
| WO-2003095665-A2 | PMEA AND PMPA CYCLIC PRODUCING SYNTHESIS | METABASIS THERAPEUTICS, INC. (US) | 2003-11-20 | — | — | WO | claimed |
| EP-0087853-B1 | 4-DIPHENYLMETHYL-1-(OXOALKYL)IMINO)METHYL-PIPERIDINES AND THEIR DERIVATIVES | McNeilab, Inc. (US) | 1986-04-30 | — | — | EP | claimed |
| EP-0087853-A2 | 4-Diphenylmethyl-1-(oxoalkyl)imino)methyl-piperidines and their derivatives | McNeilab, Inc. (US) | 1983-09-07 | — | — | EP | claimed |
| US-4251655-A | GASTRIC ACID ANTISECRETORY AGENTS | MCNEILAB, INC. (US) | 1981-02-17 | — | — | US | claimed |
| CN-118324741-A | Pyrazole ether compound as well as preparation method and application thereof | 南通泰禾化工股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-3666770-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS CDK8/19 INHIBITORS | Joint Stock Company "Biocad" (RU) | 2020-06-17 | — | — | EP | disclosed |
| US-4251655-A | GASTRIC ACID ANTISECRETORY AGENTS | MCNEILAB, INC. (US) | 1981-02-17 | — | — | US | disclosed |
| US-4251655-A | GASTRIC ACID ANTISECRETORY AGENTS | MCNEILAB, INC. (US) | 1981-02-17 | — | — | US | disclosed |
| US-4251655-A | GASTRIC ACID ANTISECRETORY AGENTS | MCNEILAB, INC. (US) | 1981-02-17 | — | — | US | disclosed |