Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.53 |
| ▸ | CNR1 | P21554 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1876102 | 0.88 | CNR2 (0.38) | CNR2CNR1SMN1; SMN2LMNA | |
| SCHEMBL1464477 | 0.80 | CNR2 (0.54) | CNR2CNR1SMN1; SMN2 | |
| SCHEMBL1463816 | 0.78 | CNR2 (0.57) | CNR2CNR1SMN1; SMN2MAPK14 | |
| SCHEMBL3963538 | 0.78 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL12095585 | 0.76 | CNR2 (0.59) | CNR2CNR1MAPK14 | |
| SCHEMBL1464614 | 0.73 | CNR2 (0.73) | CNR2CNR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3968895 | 0.73 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL1463932 | 0.73 | CNR2 (0.72) | CNR2CNR1SMN1; SMN2MAPK14CYP2C8 | |
| SCHEMBL469406 | 0.72 | CNR2 (1.00) | CNR2CNR1MAPK14CYP2C8CYP2C9 | |
| SCHEMBL3960778 | 0.71 | CNR2 (0.55) | CNR2CNR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |