Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464511 | 0.95 | CNR2 (0.50) | CNR2TP53MAPTSMN1; SMN2LMNA | |
| SCHEMBL1464409 | 0.87 | CNR2 (0.75) | CNR2MAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL3968208 | 0.85 | CNR2 (0.62) | CNR2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL1464509 | 0.84 | CNR2 (0.66) | CNR2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL1464386 | 0.80 | CNR2 (0.53) | CNR2MAPTRAB9A | |
| SCHEMBL3964897 | 0.80 | CNR2 (0.59) | CNR2MAPT | |
| SCHEMBL1620976 | 0.78 | CNR2 (0.43) | CNR2MAPTSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL3962989 | 0.77 | CNR2 (0.53) | CNR2MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL1464598 | 0.76 | CNR2 (0.78) | CNR2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL1464857 | 0.76 | CNR2 (0.82) | CNR2MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |