SCHEMBL3969378

SCHEMBL3969378

Cc1ccc(Cn2c(NCc3ccccc3)nc3nc(N4CCCC(N)C4)n(Cc4ccccc4)c3c2=O)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.51
FAP Q12884 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3971411 0.91 DPP4 (0.56) DPP4FAP
SCHEMBL3966118 0.87 DPP4 (0.51) DPP4FAP
SCHEMBL3971487 0.86 DPP4 (0.58) DPP4FAP
SCHEMBL4082595 0.85 DPP4 (0.53) DPP4FAP
SCHEMBL3967659 0.85 DPP4 (0.60) DPP4FAP
SCHEMBL3969500 0.85 DPP4 (0.54) DPP4FAP
SCHEMBL3967148 0.85 DPP4 (0.54) DPP4FAP
SCHEMBL3970558 0.85 DPP4 (0.52) DPP4FAP
SCHEMBL3970033 0.84 DPP4 (0.58) DPP4FAP
SCHEMBL3966257 0.84 DPP4 (0.65) DPP4FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569574-B2 Purine derivatives, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2009-08-04 US disclosed
EP-1532150-B1 NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA (DE) 2008-06-11 EP disclosed
EP-1532150-A1 NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2005-05-25 EP disclosed
WO-2004018469-A1 NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2004-03-04 WO disclosed