SCHEMBL3970464

SCHEMBL3970464

Cc1cc(C2CC(c3nc(C(C)C)no3)CN(C=O)C2)ccc1OC(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.36
F2R P25116 1/20 0.36
TMEM97 Q5BJF2 1/20 0.36
EPHX2 P34913 1/20 0.36
CNR2 P34972 1/20 0.35
HCRTR1 O43613 6/20 0.33
HCRTR2 O43614 6/20 0.33
GPR119 Q8TDV5 1/20 0.33
GRM2 Q14416 3/20 0.33
SCN5A Q14524 1/20 0.32
ENPP2 Q13822 2/20 0.32
CHRM4 P08173 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2965835 0.86 F2R (0.48) CNR1F2RTMEM97EPHX2CNR2
Hydrochloric Acid SCHEMBL3974288 0.85 F2R (0.47) CNR1F2RTMEM97EPHX2CNR2
SCHEMBL3970526 0.84 CNR1 (0.34) CNR1F2RTMEM97HCRTR1HCRTR2
SCHEMBL641366 0.83 F2R (0.48) CNR1F2RTMEM97EPHX2GPR119
SCHEMBL1581957 0.83 F2R (0.49) CNR1F2RTMEM97EPHX2HCRTR1
SCHEMBL2975547 0.81 EPHX2 (0.40) CNR1F2RTMEM97EPHX2CNR2
SCHEMBL3968395 0.79 EPHX2 (0.42) EPHX2CNR2HCRTR1HCRTR2GRM2
SCHEMBL2963821 0.77 F2R (0.50) CNR1F2RTMEM97EPHX2HCRTR1
Hydrochloric Acid SCHEMBL3973429 0.76 F2R (0.49) CNR1F2RTMEM97EPHX2HCRTR1
SCHEMBL3971593 0.71 F2R (0.65) CNR1F2RTMEM97HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090306139-A1 HETEROARYL-SUBSTITUTED PIPERIDINES BAYER HEALTHCARE AG (DE) 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306139-A1 HETEROARYL-SUBSTITUTED PIPERIDINES VHL, PIGO, PLIN3 CNR1 454/4885F2R 698/4885TMEM97 1110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.