Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.69 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970596 | 1.00 | ABCG2 (0.70) | ABCG2PTGS1PTGS2CYP1A1CYP1B1 | |
| SCHEMBL498717 | 0.91 | ABCG2 (0.66) | ABCG2PTGS1PTGS2BCHEACHE | |
| SCHEMBL498718 | 0.91 | ABCG2 (0.66) | ABCG2PTGS1PTGS2BCHEACHE | |
| SCHEMBL3969188 | 0.91 | ABCG2 (0.66) | ABCG2PTGS1PTGS2BCHEACHE | |
| SCHEMBL4217390 | 0.91 | ABCG2 (0.66) | ABCG2PTGS1PTGS2BCHEACHE | |
| SCHEMBL3969259 | 0.91 | ABCG2 (0.66) | ABCG2PTGS1PTGS2BCHEACHE | |
| SCHEMBL3969187 | 0.91 | ABCG2 (0.66) | ABCG2PTGS1PTGS2BCHEACHE | |
| SCHEMBL3969256 | 0.91 | ABCG2 (0.66) | ABCG2PTGS1PTGS2BCHEACHE | |
| SCHEMBL4217391 | 0.91 | ABCG2 (0.66) | ABCG2PTGS1PTGS2BCHEACHE | |
| SCHEMBL13764738 | 0.90 | MAOB (0.69) | ABCG2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566737-B2 | Combinations of substituted 1,3-diphenylprop-2-en-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2009-07-28 | — | — | US | disclosed |
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | PSEN1, BACE1, PSEN2 | ABCG2 2957/4885PTGS1 98/4885PTGS2 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.