SCHEMBL3970764

SCHEMBL3970764

CCCCCc1nc2c(N)nc3ccccc3c2n1CCCCN

nearest known ligand 0.94

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 18/20 0.94
TLR8 Q9NR97 8/20 0.94

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5122398 0.97 TLR7 (0.91) TLR7TLR8
SCHEMBL1615627 0.97 TLR7 (1.00) TLR7TLR8
SCHEMBL3863599 0.96 TLR7 (0.98) TLR7TLR8
SCHEMBL1951699 0.93 TLR7 (0.93) TLR7TLR8
SCHEMBL1615906 0.93 TLR7 (0.89) TLR7TLR8
SCHEMBL20623370 0.93 TLR7 (0.89) TLR7TLR8
SCHEMBL18645633 0.91 TLR7 (0.88) TLR7TLR8
SCHEMBL3817941 0.90 TLR7 (0.87) TLR7TLR8
SCHEMBL1950357 0.90 TLR7 (0.83) TLR7TLR8
SCHEMBL18646022 0.89 TLR7 (0.84) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1638566-A4 SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2009-03-25 EP disclosed
EP-1638566-A2 SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M Innovative Properties Company (US) 2006-03-29 EP disclosed
WO-2005003064-A2 SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-01-13 WO disclosed
WO-2005003065-A2 SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-01-13 WO disclosed