Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970569 | 0.90 | F2R (0.44) | EPHX2KCNH2GRM5SCD5ABL1 | |
| SCHEMBL1581145 | 0.83 | EPHX2 (0.48) | EPHX2KCNH2GRM5CNR1F2R | |
| SCHEMBL10234613 | 0.81 | F2R (0.48) | EPHX2KCNH2GRM5CNR1F2R | |
| SCHEMBL3969596 | 0.75 | F2R (0.47) | GRM5CNR1F2RTMEM97ALDH1A1 | |
| SCHEMBL3972754 | 0.75 | GRM5 (0.48) | GRM5CNR1F2RTMEM97 | |
| SCHEMBL1580726 | 0.73 | F2R (0.58) | EPHX2KCNH2GRM5ABL1CNR1 | |
| SCHEMBL3975115 | 0.73 | EPHX2 (0.55) | EPHX2KCNH2GRM5NPC1ALDH1A1 | |
| SCHEMBL641076 | 0.71 | F2R (0.56) | EPHX2KCNH2GRM5CNR1F2R | |
| SCHEMBL2963821 | 0.71 | F2R (0.50) | EPHX2KCNH2CNR1F2RTMEM97 | |
| Hydrochloric Acid SCHEMBL3973429 | 0.70 | F2R (0.49) | EPHX2KCNH2CNR1F2RTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306139-A1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER HEALTHCARE AG (DE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306139-A1 | HETEROARYL-SUBSTITUTED PIPERIDINES | VHL, PIGO, PLIN3 | EPHX2 1595/4885KCNH2 1272/4885GRM5 1833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.