Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972767 | 1.00 | TLR4 (0.48) | TLR4TLR2SLC2A1MAOAMAOB | |
| SCHEMBL3969096 | 0.98 | TLR4 (0.46) | TLR4TLR2SLC2A1MAOAMAOB | |
| SCHEMBL3969111 | 0.95 | ACACB (0.46) | TLR4TLR2SLC2A1PARP15PARP10 | |
| SCHEMBL8274392 | 0.92 | CNR1 (0.45) | TLR4TLR2 | |
| SCHEMBL4568750 | 0.92 | SLC2A1 (0.48) | TLR4TLR2SLC2A1MAOAMAOB | |
| SCHEMBL3967742 | 0.92 | SLC2A1 (0.48) | TLR4TLR2SLC2A1MAOAMAOB | |
| SCHEMBL4568833 | 0.92 | SLC2A1 (0.48) | TLR4TLR2SLC2A1MAOAMAOB | |
| SCHEMBL4568850 | 0.90 | PPARA (0.53) | TLR4TLR2SLC2A1 | |
| SCHEMBL4568811 | 0.90 | PPARA (0.49) | TLR4TLR2SLC2A1 | |
| SCHEMBL24196243 | 0.88 | KDM4E (0.51) | TLR4TLR2SLC2A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091955-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | Acucela, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |