⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23297342 | 0.88 | TSHR (0.32) | — | |
| SCHEMBL3447447 | 0.76 | — | — | |
| SCHEMBL8602409 | 0.71 | — | — | |
| SCHEMBL4454495 | 0.71 | — | — | |
| SCHEMBL6887990 | 0.69 | — | — | |
| SCHEMBL933002 | 0.69 | — | — | |
| SCHEMBL808507 | 0.69 | — | — | |
| SCHEMBL11852450 | 0.69 | — | — | |
| SCHEMBL28062824 | 0.69 | — | — | |
| SCHEMBL17376783 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2736506-B1 | MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER | UNIV SOUTHERN CALIFORNIA (US) | 2018-09-05 | — | — | EP | disclosed |
| US-20180185303-A1 | MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2018-07-05 | — | — | US | disclosed |
| US-9771625-B2 | Monoamine oxidase inhibitors and methods for treatment and diagnosis of prostate cancer | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-09-26 | — | — | US | disclosed |
| EP-2736506-A2 | MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER | University Of Southern California (US) | 2014-06-04 | — | — | EP | disclosed |
| EP-1112254-B1 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN LIFE SCIENCE PROD INC (US) | 2013-02-27 | — | — | EP | disclosed |
| US-20130039854-A1 | MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-02-14 | — | — | US | disclosed |
| WO-2013016580-A2 | MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-01-31 | — | — | WO | disclosed |
| US-7524942-B2 | Labeled nucleotide composition | AGILENT TECHNOLOGIES, INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-20080124708-A1 | Labeled nucleotide composition | AGILENT TECHNOLOGIES, INC. | 2008-05-29 | — | — | US | disclosed |
| EP-1112254-A4 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN LIFE SCIENCE PROD INC (US) | 2005-03-16 | — | — | EP | disclosed |
| US-6437141-B2 | FOR LABELING TARGET MOLECULES | NEN LIFE SCIENCE PRODUCTS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-20010020098-A1 | For labeling target molecules | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-09-06 | — | — | US | disclosed |
| EP-1112254-A2 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN Life Science Products, Inc. (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6224644-B1 | CYANINE DYES INCLUDES FREE OR PROTECTED THIOL, AMINE OR HYDROXY SUBSTITUENT CAPABLE OF REACTING WITH A TARGET MOLECULE THROUGH A NEUCLOPHILIC DISPLACEMENT, USEFUL IN LABELING A VARIETY OF TARGET MOLECULES | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-05-01 | — | — | US | disclosed |
| US-6204389-B1 | DEBLOCKING; NUCLEOPHILIC DISPLACEMENT | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-03-20 | — | — | US | disclosed |
| US-6197956-B1 | FLUORESCENT BENZIMIDAZOLE, BENZOTHIAZOLE, BENZOXAZOLE, BENZOTHIAZINE, BENZOXAZINE AND QUINOLINE DYES | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-03-06 | — | — | US | disclosed |
| WO-2000063296-A2 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-10-26 | — | — | WO | disclosed |
| US-6114350-A | Cyanine dyes and synthesis methods thereof | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-09-05 | — | — | US | disclosed |