Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3971380 | 0.92 | DPP4 (0.40) | DPP4CHRM1KCNH2 | |
| SCHEMBL3973726 | 0.91 | DPP4 (0.39) | DPP4 | |
| SCHEMBL3971268 | 0.89 | DPP4 (0.38) | DPP4KCNH2 | |
| SCHEMBL3975266 | 0.89 | DPP4 (0.39) | DPP4KCNH2 | |
| SCHEMBL3965788 | 0.88 | DPP4 (0.36) | DPP4 | |
| SCHEMBL3971303 | 0.88 | DPP4 (0.37) | DPP4AADATKCNH2 | |
| SCHEMBL1071796 | 0.88 | DPP4 (0.37) | DPP4AADAT | |
| SCHEMBL3973460 | 0.86 | TP53 (0.38) | DPP4 | |
| SCHEMBL3971754 | 0.85 | DPP4 (0.35) | DPP4KCNH2 | |
| SCHEMBL3975232 | 0.85 | MAPT (0.38) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569574-B2 | Purine derivatives, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2009-08-04 | — | — | US | disclosed |