Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 5/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740055 | 0.89 | HMGCR (0.41) | ABCC3ABCC4HMGCRHDAC1HDAC2 | |
| SCHEMBL1739610 | 0.88 | ABCC3 (0.43) | ABCC3ABCC4HMGCRHDAC1HDAC2 | |
| Zinc Ion SCHEMBL1741829 | 0.88 | ABCC3 (0.42) | ABCC3ABCC4HMGCRHDAC1HDAC2 | |
| SCHEMBL2684321 | 0.88 | ABCC3 (0.42) | ABCC3ABCC4HMGCRHDAC1HDAC2 | |
| Tert-Butylamine SCHEMBL1739620 | 0.88 | HMGCR (0.40) | ABCC3ABCC4HMGCRHDAC1HDAC2 | |
| SCHEMBL3968201 | 0.78 | HMGCR (0.43) | ABCC3ABCC4HMGCRHDAC1HDAC2 | |
| SCHEMBL17965919 | 0.78 | HMGCR (0.43) | ABCC3ABCC4HMGCRHDAC1HDAC2 | |
| SCHEMBL1740202 | 0.78 | HMGCR (0.43) | ABCC3ABCC4HMGCRHDAC1HDAC2 | |
| SCHEMBL16401134 | 0.77 | ABCC3 (0.53) | ABCC3ABCC4HMGCRHDAC1HDAC2 | |
| SCHEMBL3305 | 0.77 | ABCC3 (0.57) | ABCC3ABCC4HMGCRHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047577-A1 | PROCESS FOR PREPARATION OF ROSUVASTATIN ZINC SALT | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársaság (HU) | 2009-04-16 | — | — | WO | disclosed |