SCHEMBL3971743

SCHEMBL3971743

Oc1ccc(C2(c3ccc(O)c(-c4cccc5ccccc45)c3)C3CC4CC(C3)CC2C4)cc1-c1cccc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.37
ACMSD Q8TDX5 1/20 0.37
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 2/20 0.35
CHRNA1 P02708 1/20 0.35
CHRNG P07510 1/20 0.35
CHRNB1 P11230 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35
CHRND Q07001 1/20 0.35
DHFR P00374 2/20 0.34
CYP1A2 P05177 1/20 0.34
POLB P06746 2/20 0.34
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
GFER P55789 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3976009 0.81 MEN1 (0.46) MCL1ACMSDDHFRCYP1A2POLB
SCHEMBL3980599 0.79 BACE1 (0.44) POLBMEN1GAAGFERKMT2A
SCHEMBL5465904 0.73 ESR1 (0.56) MCL1ACMSDDHFRCYP1A2POLB
SCHEMBL3754199 0.73 MEN1 (0.59) POLBMEN1GAAGFERKMT2A
SCHEMBL23627814 0.72 MAPT (0.41) SLC6A2SLC6A4SLC6A3CHRNA1CHRNG
SCHEMBL26153496 0.71 CYP1A2 (0.58) MCL1ACMSDCYP1A2POLBMEN1
SCHEMBL93762 0.70 ESR2 (0.50) MCL1ACMSDCYP1A2POLBMEN1
SCHEMBL3976002 0.69 MEN1 (0.42) DHFRPOLBMEN1GAAGFER
SCHEMBL1238135 0.69 ESR1 (0.50) POLBMEN1GAAGFERKMT2A
SCHEMBL3974982 0.69 MEN1 (0.42) DHFRPOLBMEN1GAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed