Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885852 | 0.93 | EGLN1 (0.59) | EGLN1 | |
| SCHEMBL2887549 | 0.91 | EGLN1 (0.63) | EGLN1 | |
| SCHEMBL3972491 | 0.88 | EGLN1 (0.48) | EGLN1 | |
| SCHEMBL2884030 | 0.82 | EGLN1 (0.60) | EGLN1 | |
| SCHEMBL2888776 | 0.82 | EGLN1 (0.77) | EGLN1 | |
| SCHEMBL2889304 | 0.79 | EGLN1 (0.62) | EGLN1 | |
| SCHEMBL2881515 | 0.77 | EGLN1 (0.58) | EGLN1 | |
| SCHEMBL12502724 | 0.77 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL2884028 | 0.76 | ELANE (0.46) | — | |
| SCHEMBL2880481 | 0.75 | EGLN1 (0.63) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016078-A2 | PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | FIBROGEN, INC. (US) | 2009-01-21 | — | — | EP | claimed |
| WO-2007115315-A2 | PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | FIBROGEN, INC. (US) | 2007-10-11 | — | — | WO | claimed |