Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093706 | 0.84 | MAPT (0.55) | ATMIDO1TDO2ALDH1A1GAA | |
| SCHEMBL6674552 | 0.70 | ATM (0.39) | ATMIDO1TDO2ALDH1A1GAA | |
| SCHEMBL11801695 | 0.70 | HSD17B10 (0.47) | ATMIDO1TDO2ALDH1A1GAA | |
| SCHEMBL1461839 | 0.67 | MAPT (0.56) | IDO1TDO2ALDH1A1GAAMAPT | |
| SCHEMBL9206122 | 0.67 | MAPT (0.41) | IDO1TDO2ALDH1A1MAPTLMNA | |
| SCHEMBL30250175 | 0.66 | ATM (0.61) | ATMALDH1A1GAALMNAKMT2A | |
| SCHEMBL3143561 | 0.66 | ATM (0.61) | ATMALDH1A1GAALMNAKMT2A | |
| SCHEMBL5737972 | 0.66 | MAPT (0.55) | IDO1TDO2ALDH1A1GAAMAPT | |
| SCHEMBL6297845 | 0.66 | MAPT (0.59) | IDO1TDO2ALDH1A1GAAMAPT | |
| SCHEMBL8645020 | 0.65 | GSK3B (0.43) | ATMIDO1TDO2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053799-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-04-30 | — | — | WO | disclosed |