Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4505040 | 0.92 | MAP2K1 (1.00) | MAP2K2MAP2K1 | |
| SCHEMBL4497546 | 0.90 | MAP2K1 (0.83) | MAP2K2MAP2K1 | |
| SCHEMBL4508839 | 0.90 | MAP2K1 (0.81) | MAP2K2MAP2K1 | |
| SCHEMBL4511989 | 0.89 | MAP2K1 (0.84) | MAP2K2MAP2K1 | |
| SCHEMBL4501703 | 0.89 | MAP2K2 (0.79) | MAP2K2MAP2K1 | |
| SCHEMBL4019351 | 0.88 | MAP2K2 (1.00) | MAP2K2MAP2K1 | |
| SCHEMBL4498410 | 0.88 | MAP2K2 (0.80) | MAP2K2MAP2K1 | |
| SCHEMBL4516941 | 0.87 | MAP2K2 (0.82) | MAP2K2MAP2K1 | |
| SCHEMBL4511537 | 0.87 | MAP2K1 (0.77) | MAP2K2MAP2K1 | |
| SCHEMBL4498061 | 0.87 | MAP2K2 (0.81) | MAP2K2MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264411-A1 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2009-10-22 | — | — | US | claimed |
| US-20090264411-A1 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2009-10-22 | — | — | US | disclosed |
| EP-2054417-A2 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | UCB Pharma S.A. (BE) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008020206-A2 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264411-A1 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | MAPK15, MOK, MAPK14 | MAP2K2 9/4885MAP2K1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.