SCHEMBL3973537

SCHEMBL3973537

Nc1cc(-c2ccc([N+](=O)[O-])c(N)c2)ccc1[N+](=O)[O-]

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.69
TDP1 Q9NUW8 5/20 0.69
MEN1 O00255 4/20 0.69
KMT2A Q03164 4/20 0.69
TSHR P16473 3/20 0.69
POLB P06746 3/20 0.69
ALDH1A1 P00352 4/20 0.53
LMNA P02545 3/20 0.53
CYP3A4 P08684 2/20 0.52
ALOX15 P16050 2/20 0.52
MAPK1 P28482 2/20 0.51
RECQL P46063 2/20 0.49
SIRT6 Q8N6T7 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.46
MCL1 Q07820 1/20 0.46
PKM P14618 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31570099 0.90 MAPT (0.58) MAPTTDP1MEN1KMT2ATSHR
SCHEMBL720554 0.90 MAPT (0.58) MAPTTDP1MEN1KMT2ATSHR
SCHEMBL10714696 0.90 TDP1 (0.63) MAPTTDP1MEN1KMT2ATSHR
SCHEMBL20788508 0.89 MAPT (0.56) MAPTTDP1MEN1KMT2ATSHR
SCHEMBL8587439 0.89 MAPT (0.56) MAPTTDP1MEN1KMT2ATSHR
SCHEMBL13735059 0.89 MAPT (0.56) MAPTTDP1MEN1KMT2ATSHR
SCHEMBL13735401 0.87 MAPT (0.55) MAPTTDP1MEN1KMT2ATSHR
SCHEMBL8291368 0.84 MAPT (0.51) MAPTTDP1MEN1KMT2ATSHR
SCHEMBL11220965 0.84 MAPT (0.51) MAPTTDP1MEN1KMT2ATSHR
SCHEMBL4581172 0.84 MAPT (0.51) MAPTTDP1MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1727781-B1 PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL COUNCIL SCIENT IND RES (IN) 2009-05-06 EP claimed
US-5276132-A Polyamic acid or polyimide having a steroidal skeleton providing a pretilt angle of 3 to 90 degrees; SBE(super twisted birefringence effect) and SH(super homeotropic) devices JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-01-04 US claimed
EP-4724543-A1 IRIDIUM COMPLEXES USED AS PHOTOSENSITIZERS Université Grenoble Alpes (FR) 2026-04-15 EP disclosed
WO-2024256777-A1 IRIDIUM COMPLEXES USED AS PHOTOSENSITIZERS UNIVERSITE GRENOBLE ALPES (FR) 2024-12-19 WO disclosed
EP-1727781-B1 PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL COUNCIL SCIENT IND RES (IN) 2009-05-06 EP disclosed
EP-1727781-B1 PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL COUNCIL SCIENT IND RES (IN) 2009-05-06 EP disclosed
EP-1727781-B1 PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL COUNCIL SCIENT IND RES (IN) 2009-05-06 EP disclosed
EP-1727781-A1 PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL Council of Scientific and Industrial Research (IN) 2006-12-06 EP disclosed
EP-1727781-A1 PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL Council of Scientific and Industrial Research (IN) 2006-12-06 EP disclosed
WO-2005063679-A1 PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-07-14 WO disclosed
WO-2005063679-A1 PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-07-14 WO disclosed
US-6835854-B1 Oxidation of 3,3'-dichloro 4,4'-diaminobiphenyl (DCB), ammonolysis of the resulting 3,3'-dichloro-4,4'-dinitrobiphenyl (DCDNB) and reduction of 3,3'-diamino-4,4'-dinitrobiphenyl and treating with an alkali COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-12-28 US disclosed
US-6835854-B1 Oxidation of 3,3'-dichloro 4,4'-diaminobiphenyl (DCB), ammonolysis of the resulting 3,3'-dichloro-4,4'-dinitrobiphenyl (DCDNB) and reduction of 3,3'-diamino-4,4'-dinitrobiphenyl and treating with an alkali COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-12-28 US disclosed
EP-0503918-B1 Liquid crystal aligning agent and aligning agent-applied liquid crystal display device JAPAN SYNTHETIC RUBBER CO LTD (JP) 1995-12-27 EP disclosed
US-5276132-A Polyamic acid or polyimide having a steroidal skeleton providing a pretilt angle of 3 to 90 degrees; SBE(super twisted birefringence effect) and SH(super homeotropic) devices JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-01-04 US disclosed
WO-1992015919-A1 LIQUID CRYSTAL ALIGNING AGENT AND ALIGNING AGENT-APPLIED LIQUID CRYSTAL DISPLAY DEVICE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-09-17 WO disclosed
EP-0503918-A1 Liquid crystal aligning agent and aligning agent-applied liquid crystal display device JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-09-16 EP disclosed