Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MGAM | O43451 | 3/20 | 0.35 |
| ▸ | SI | P14410 | 3/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801810 | 0.81 | GAA (0.44) | GAAMGAMSIMGAM2LMNA | |
| SCHEMBL30058937 | 0.81 | GAA (0.44) | GAAMGAMSIMGAM2LMNA | |
| SCHEMBL11468152 | 0.78 | MAPT (0.36) | GAAMGAMSIMGAM2LMNA | |
| SCHEMBL3974124 | 0.77 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL15766019 | 0.77 | MAPT (0.41) | GAAMGAMSIMGAM2LMNA | |
| SCHEMBL29501455 | 0.76 | MGAM (0.43) | GAAMGAMSIMGAM2TP53 | |
| SCHEMBL83054 | 0.76 | MGAM (0.43) | GAAMGAMSIMGAM2TP53 | |
| SCHEMBL4025305 | 0.75 | KIT (0.35) | GAAMGAMSIMGAM2LMNA | |
| SCHEMBL4073935 | 0.75 | KMT2A (0.43) | GAAMGAMSIMGAM2LMNA | |
| SCHEMBL28889443 | 0.75 | ELANE (0.38) | GAAMGAMSIMGAM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828270-B1 | NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECHNOLOGIES INC (US) | 2013-04-10 | — | — | EP | claimed |
| EP-1664855-B1 | PROCESS FOR MANUFACTURING INTRAOCULAR LENSES WITH BLUE LIGHT ABSORPTION CHARACTERISTICS | BAUSCH & LOMB (US) | 2009-03-11 | — | — | EP | claimed |