SCHEMBL3974377

SCHEMBL3974377

Nc1cc(N)nc(O)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29822342 1.00
SCHEMBL7690577 0.85
SCHEMBL1317980 0.78
SCHEMBL7697864 0.78
SCHEMBL19433170 0.74
SCHEMBL14920610 0.74
SCHEMBL10792756 0.74
SCHEMBL19327477 0.74
SCHEMBL94169 0.72
SCHEMBL29585390 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117322429-A Eucalyptus growth inhibitor, preparation method thereof and application thereof in power line protection area 广东电网有限责任公司 2024-01-02 CN claimed
CN-117322429-A Eucalyptus growth inhibitor, preparation method thereof and application thereof in power line protection area 广东电网有限责任公司 2024-01-02 CN disclosed
CN-117322429-A Eucalyptus growth inhibitor, preparation method thereof and application thereof in power line protection area 广东电网有限责任公司 2024-01-02 CN disclosed
CN-114965738-A HPLC-UV detection method for purity of 2,4-diamino-6-hydroxypyrimidine starting material 汉瑞药业(荆门)有限公司 2022-08-30 CN disclosed
EP-2386558-A1 CGRP antagonists Boehringer Ingelheim International GmbH (DE) 2011-11-16 EP disclosed
US-7531164-B2 Preventing bacterial or viral infectivity and composition containing infection preventing additive DUKE UNIVERSITY (US) 2009-05-12 US disclosed
WO-2007050379-A2 PREVENTING BACTERIAL OR VIRAL INFECTIVITY AND COMPOSITION CONTAINING INFECTION PREVENTING ADDITIVE DUKE UNIVERSITY (US) 2007-05-03 WO disclosed
US-20070092512-A1 Preventing bacterial or viral infectivity and composition containing infection preventing additive DUKE UNIVERSITY (US) 2007-04-26 US disclosed
US-6274581-B1 Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis CORNELL RESEARCH FOUNDATION, INC. 2001-08-14 US disclosed
US-6153615-A Blocking induction of tetrahydrobioterin to block induction of nitric oxide synthesis CORNELL RESEARCH FOUNDATION, INC. (US) 2000-11-28 US disclosed
US-5880124-A Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis CORNELL RESEARCH FOUNDATION, INC. (US) 1999-03-09 US disclosed
US-5877176-A Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis CORNELL RESEARCH FOUNDATION, INC. (US) 1999-03-02 US disclosed