Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.80 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.80 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.80 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174966 | 0.94 | PDE4A (0.82) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3169940 | 0.90 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL3166204 | 0.90 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3166307 | 0.90 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3179852 | 0.89 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3174850 | 0.89 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3167276 | 0.87 | PDE4A (0.96) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3176481 | 0.86 | PDE4A (0.83) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL3160530 | 0.86 | PDE4A (0.82) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3170369 | 0.83 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1308440-B1 | PIPERIDINE DERIVATIVES AND DRUGS CONTAINING THESE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2009-05-06 | — | — | EP | claimed |
| EP-1308440-A1 | PIPERIDINE DERIVATIVES AND DRUGS CONTAINING THESE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-05-07 | — | — | EP | claimed |
| US-7649095-B2 | Piperidine derivatives and agent comprising the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-01-19 | — | — | US | disclosed |
| EP-1308440-B1 | PIPERIDINE DERIVATIVES AND DRUGS CONTAINING THESE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2009-05-06 | — | — | EP | disclosed |