SCHEMBL3974556

SCHEMBL3974556

CN(C(=O)OC(C)(C)C)c1ccc(C=Cc2ccc(OCCOCCOCCOCCOCCF)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APP P05067 11/20 0.52
PPARA Q07869 5/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2836057 1.00 APP (0.52) APPPPARA
SCHEMBL2836055 1.00 APP (0.52) APPPPARA
SCHEMBL3974555 1.00 APP (0.52) APPPPARA
SCHEMBL2829939 1.00 APP (0.52) APPPPARA
SCHEMBL2829935 1.00 APP (0.52) APPPPARA
SCHEMBL2829944 1.00 APP (0.52) APPPPARA
SCHEMBL13328310 1.00 APP (0.52) APPPPARA
SCHEMBL2833682 0.92 APP (0.48) APPPPARA
SCHEMBL1421269 0.92 APP (0.48) APPPPARA
SCHEMBL2831861 0.92 APP (0.48) APPPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1841465-A4 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES UNIV PENNSYLVANIA (US) 2009-04-01 EP disclosed
EP-1838298-A4 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES UNIV PENNSYLVANIA (US) 2009-03-04 EP disclosed
EP-1841465-A2 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES The Trustees of The University of Pennsylvania (US) 2007-10-10 EP disclosed
EP-1838298-A2 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES The Trustees of The University of Pennsylvania (US) 2007-10-03 EP disclosed
WO-2006078384-A2 STILBENE DERIVATIVES AND THEIR USE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2006-07-27 WO disclosed
WO-2006066104-A2 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2006-06-22 WO disclosed