Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.54 |
| ▸ | CFTR | P13569 | 3/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24413993 | 0.87 | CFTR (0.58) | GAACFTRNQO2CA12CA1 | |
| SCHEMBL2701033 | 0.85 | GAA (0.61) | GAACFTRCA12CA1CA2 | |
| SCHEMBL18863815 | 0.83 | GAA (0.59) | GAACFTRCA12CA1CA2 | |
| SCHEMBL29370673 | 0.83 | GAA (0.59) | GAACFTRCA12CA1CA2 | |
| SCHEMBL29790105 | 0.82 | KDM4E (0.50) | GAACFTRNQO2KDM4EALDH1A1 | |
| SCHEMBL2690892 | 0.82 | KDM4E (0.50) | GAACFTRNQO2KDM4EALDH1A1 | |
| SCHEMBL31515143 | 0.81 | GAA (0.53) | GAACFTRNQO2KDM4EALDH1A1 | |
| SCHEMBL23874532 | 0.81 | GAA (0.61) | GAACFTRNQO2KDM4EALDH1A1 | |
| SCHEMBL23536211 | 0.81 | NQO2 (0.49) | GAACFTRNQO2CA1CA2 | |
| SCHEMBL30064505 | 0.81 | NQO2 (0.49) | GAACFTRNQO2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049098-A2 | MATERIALS AND METHODS FOR REGULATING THE ACTIVITY OF PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |