Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11793423 | 0.77 | MEN1 (0.35) | KMT2AMEN1BLMPEPDMCL1 | |
| SCHEMBL1306142 | 0.77 | KMT2A (0.35) | KMT2AMEN1BLMPEPDGRM4 | |
| SCHEMBL9541416 | 0.77 | CA1 (0.40) | KMT2AMCL1KDM4EPOLBL3MBTL1 | |
| SCHEMBL1234936 | 0.74 | KDM4E (0.36) | KMT2AMEN1BLMPEPDKDM4E | |
| SCHEMBL1879279 | 0.73 | CYP2C19 (0.35) | KMT2AMEN1BLMMCL1KDM4E | |
| SCHEMBL7337219 | 0.72 | NPC1 (0.36) | KMT2AMCL1KDM4EL3MBTL1CA1 | |
| SCHEMBL27564747 | 0.72 | MEN1 (0.32) | KMT2AMEN1BLMPEPDKDM4E | |
| SCHEMBL932332 | 0.70 | — | — | |
| SCHEMBL22468834 | 0.70 | — | — | |
| SCHEMBL22612515 | 0.69 | KMT2A (0.50) | KMT2AMCL1KDM4EPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| US-4029687-A | HERBICIDES | CIBA-GEIGY AG (CH) | 1977-06-14 | — | — | US | disclosed |
| US-4004914-A | HERBICIDES | CIBA-GEIGY AG (CH) | 1977-01-25 | — | — | US | disclosed |