⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140384 | 0.82 | — | — | |
| SCHEMBL30285919 | 0.79 | — | — | |
| SCHEMBL3235191 | 0.70 | — | — | |
| SCHEMBL3572842 | 0.70 | — | — | |
| SCHEMBL3231204 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL28576918 | 0.67 | — | — | |
| SCHEMBL14992841 | 0.66 | — | — | |
| SCHEMBL11183037 | 0.66 | — | — | |
| SCHEMBL28716421 | 0.65 | — | — | |
| SCHEMBL28168516 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1691800-A4 | METHODS AND AGENTS FOR INHIBITING DYNAMIN-DEPENDENT ENDOCYTOSIS | UNIV NEWCASTLE RES ASS (AU) | 2009-03-18 | — | — | EP | disclosed |
| US-20070225363-A1 | Methods and Agents for Inhibiting Dynamin-Dependent Endocytosis | THE UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LTD. (AU) | 2007-09-27 | — | — | US | disclosed |
| EP-1691800-A1 | METHODS AND AGENTS FOR INHIBITING DYNAMIN-DEPENDENT ENDOCYTOSIS | THE UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LIMITED (AU) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005049009-A1 | METHODS AND AGENTS FOR INHIBITING DYNAMIN-DEPENDENT ENDOCYTOSIS | THE UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LIMITED (AU) | 2005-06-02 | — | — | WO | disclosed |
| WO-2001007034-A1 | MULTIDRUG RESISTANCE PUMP INHIBITORS AND USES THEREOF | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2001-02-01 | — | — | WO | disclosed |