Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 12/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | EP300 | Q09472 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972624 | 0.85 | POLB (0.55) | KMT2AHTTMEN1POLBALDH1A1 | |
| SCHEMBL3973488 | 0.82 | NR4A2 (0.51) | KMT2APOLBALDH1A1 | |
| SCHEMBL3993831 | 0.82 | NTRK1 (0.42) | KMT2AMEN1POLB | |
| SCHEMBL3990809 | 0.80 | CNR2 (0.60) | — | |
| SCHEMBL3995883 | 0.76 | CNR2 (0.55) | KMT2AALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL3981980 | 0.76 | CNR1 (0.56) | CREBBPPOLBMAPT | |
| SCHEMBL13806412 | 0.76 | CNR2 (0.47) | ALDH1A1 | |
| SCHEMBL2260028 | 0.75 | NPSR1 (0.41) | KMT2AMEN1POLBALDH1A1KDM4E | |
| SCHEMBL3990432 | 0.74 | CNR2 (0.53) | — | |
| SCHEMBL3992947 | 0.74 | POLB (0.38) | KMT2AMEN1POLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065382-A1 | CGRP antagonists | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |
| WO-2009050235-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |