Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | CDK9 | P50750 | 1/20 | 0.60 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970683 | 0.88 | ABL1 (0.59) | HDAC4HDAC6CHRNA7ABL1BCR | |
| SCHEMBL1499450 | 0.85 | MCHR1 (0.65) | MCHR1HDAC4HDAC1HDAC6ALDH1A1 | |
| SCHEMBL3973397 | 0.81 | CHRNA7 (0.55) | AURKACHRNA7ABL1BCR | |
| SCHEMBL3981035 | 0.80 | CHRNA7 (0.55) | CHRNA7ABL1BCR | |
| SCHEMBL3214773 | 0.80 | JAK2 (0.56) | MCHR1CDC7CDK19IDH1 | |
| SCHEMBL24942916 | 0.78 | CCNT1 (0.73) | CCNT1CCNA2CDK2CDK9BRAF | |
| SCHEMBL1499622 | 0.75 | MCHR1 (0.53) | MCHR1ALDH1A1IDH1ABL1BCR | |
| SCHEMBL24942665 | 0.75 | CCNT1 (1.00) | CCNT1CCNA2CDK2CDK9BRAF | |
| SCHEMBL13605511 | 0.74 | BRAF (0.60) | CCNT1CCNA2CDK2CDK9BRAF | |
| SCHEMBL20685241 | 0.74 | IDH1 (0.54) | CCNT1CCNA2CDK2CDK9MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613595-A4 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-04-01 | — | — | EP | disclosed |
| EP-1613595-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2006-01-11 | — | — | EP | disclosed |
| US-20050014753-A1 | Novel compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2005-01-20 | — | — | US | disclosed |
| WO-2004089286-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014753-A1 | Novel compounds and compositions as protein kinase inhibitors | ABL1, BCR, PDGFRA | CCNT1 925/4885CCNA2 849/4885CDK2 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.