Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3904874 | 0.89 | HTR2A (0.63) | HTR2AHTR2C | |
| SCHEMBL4697766 | 0.88 | HTR2A (0.52) | HTR2AHTR2C | |
| SCHEMBL4695188 | 0.84 | HTR2A (0.64) | HTR2AHTR2C | |
| SCHEMBL4699244 | 0.84 | HTR2A (0.65) | HTR2AHTR2C | |
| SCHEMBL4697101 | 0.83 | HTR2A (0.67) | HTR2AHTR2C | |
| Trifluoroacetic Acid SCHEMBL2064581 | 0.83 | HTR2A (0.58) | HTR2AHTR2C | |
| SCHEMBL3908797 | 0.83 | HTR2A (0.46) | HTR2AHTR2C | |
| SCHEMBL3903995 | 0.83 | HTR2A (0.46) | HTR2AHTR2C | |
| SCHEMBL4695970 | 0.82 | HTR2A (0.65) | HTR2AHTR2C | |
| SCHEMBL3977925 | 0.82 | HTR2A (0.45) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018371-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-01-28 | — | — | EP | claimed |
| WO-2007136703-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | claimed |