Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20882985 | 0.90 | MAPT (0.49) | CXCR4KMT2ASMN1; SMN2NPSR1KDM4E | |
| SCHEMBL5024861 | 0.83 | CCR1 (0.46) | CXCR4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14218357 | 0.80 | MEN1 (0.37) | CXCR4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL12660023 | 0.78 | CCR1 (0.41) | CXCR4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7658744 | 0.75 | KCNA5 (0.36) | MEN1KMT2ASMN1; SMN2NPSR1GRIN2D | |
| SCHEMBL6984577 | 0.74 | IRAK4 (0.47) | CXCR4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7027271 | 0.74 | CCR1 (0.44) | CXCR4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13936657 | 0.73 | CXCR4 (0.52) | CXCR4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6917370 | 0.72 | CXCR4 (0.47) | CXCR4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5027216 | 0.72 | TDP1 (0.59) | CXCR4KMT2ASMN1; SMN2NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547784-B2 | Methods for preparing and using a zinc complex | Koike, Tohru (JP) | 2009-06-16 | — | — | US | claimed |
| US-20080108815-A1 | Methods for preparing and using a zinc complex | TOHRU KOIKE (JP) | 2008-05-08 | — | — | US | claimed |
| US-20050038258-A1 | Zinc complexes capable of capturing substances having anionic substituents | TOHRU KOIKE (JP) | 2005-02-17 | — | — | US | claimed |
| US-7547784-B2 | Methods for preparing and using a zinc complex | Koike, Tohru (JP) | 2009-06-16 | — | — | US | disclosed |
| US-7547784-B2 | Methods for preparing and using a zinc complex | Koike, Tohru (JP) | 2009-06-16 | — | — | US | disclosed |
| US-7547784-B2 | Methods for preparing and using a zinc complex | Koike, Tohru (JP) | 2009-06-16 | — | — | US | disclosed |
| US-20080108815-A1 | Methods for preparing and using a zinc complex | TOHRU KOIKE (JP) | 2008-05-08 | — | — | US | disclosed |
| US-20080108815-A1 | Methods for preparing and using a zinc complex | TOHRU KOIKE (JP) | 2008-05-08 | — | — | US | disclosed |
| US-20080108815-A1 | Methods for preparing and using a zinc complex | TOHRU KOIKE (JP) | 2008-05-08 | — | — | US | disclosed |
| US-7358363-B2 | Zinc complexes capable of capturing substances having anionic substituents | Koike, Tohru (JP) | 2008-04-15 | — | — | US | disclosed |
| US-7358363-B2 | Zinc complexes capable of capturing substances having anionic substituents | Koike, Tohru (JP) | 2008-04-15 | — | — | US | disclosed |
| US-7358363-B2 | Zinc complexes capable of capturing substances having anionic substituents | Koike, Tohru (JP) | 2008-04-15 | — | — | US | disclosed |
| US-20050038258-A1 | Zinc complexes capable of capturing substances having anionic substituents | TOHRU KOIKE (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038258-A1 | Zinc complexes capable of capturing substances having anionic substituents | SLC39A3, SLC39A11, SLC30A6 | CXCR4 770/4885CHRM2 2232/4885CHRM4 2095/4885 |
| US-20080108815-A1 | Methods for preparing and using a zinc complex | SLC30A6, SLC30A7, CNBP | CXCR4 539/4885CHRM2 3008/4885CHRM4 2567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.