Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978233 | 1.00 | SYK (0.38) | SYKAAK1TRPA1LMNASMN1; SMN2 | |
| SCHEMBL4523758 | 0.90 | SYK (0.39) | SYKAAK1TRPA1LMNASMN1; SMN2 | |
| SCHEMBL4511910 | 0.79 | PRKD3 (0.46) | SYKLMNASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL4511913 | 0.79 | PRKD3 (0.46) | SYKLMNASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL4511916 | 0.79 | PRKD3 (0.46) | SYKLMNASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3910866 | 0.78 | SYK (0.39) | SYKAAK1TRPA1LMNASMN1; SMN2 | |
| SCHEMBL4508603 | 0.78 | SYK (0.39) | SYKAAK1TRPA1LMNASMN1; SMN2 | |
| SCHEMBL4508610 | 0.78 | SYK (0.39) | SYKAAK1TRPA1LMNASMN1; SMN2 | |
| SCHEMBL4049100 | 0.77 | AAK1 (0.43) | SYKAAK1ALDH1A1MAPTPRKD3 | |
| SCHEMBL4509993 | 0.75 | EGFR (0.43) | SYKAAK1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024333-A2 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | Cancer Research Technology Limited (GB) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007125331-A2 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-11-08 | — | — | WO | disclosed |