Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 2/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979083 | 1.00 | PRKD3 (0.41) | PRKD3PRKD1PRKD2SYKGABRG2 | |
| SCHEMBL4049100 | 0.86 | AAK1 (0.43) | PRKD3PRKD1PRKD2SYKAAK1 | |
| SCHEMBL4514127 | 0.86 | PRKD3 (0.43) | PRKD3PRKD1PRKD2SYKGABRG2 | |
| SCHEMBL4523522 | 0.79 | PRKD3 (0.61) | PRKD3PRKD1PRKD2HSD17B10ALDH1A1 | |
| SCHEMBL4523519 | 0.79 | PRKD3 (0.61) | PRKD3PRKD1PRKD2HSD17B10ALDH1A1 | |
| SCHEMBL4523515 | 0.79 | PRKD3 (0.61) | PRKD3PRKD1PRKD2HSD17B10ALDH1A1 | |
| SCHEMBL4508610 | 0.74 | SYK (0.39) | SYKGABRB2AAK1ALDH1A1ATM | |
| SCHEMBL4508603 | 0.74 | SYK (0.39) | SYKGABRB2AAK1ALDH1A1ATM | |
| SCHEMBL3910866 | 0.74 | SYK (0.39) | SYKGABRB2AAK1ALDH1A1ATM | |
| SCHEMBL4523758 | 0.72 | SYK (0.39) | SYKAAK1ALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024333-A2 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | Cancer Research Technology Limited (GB) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007125331-A2 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-11-08 | — | — | WO | disclosed |