Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 20/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 20/20 | 0.68 |
| ▸ | DRD2 | P14416 | 15/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555210 | 1.00 | DRD3 (0.68) | DRD3KCNH2DRD2CYP1A2CYP2C19 | |
| SCHEMBL3979750 | 1.00 | DRD3 (0.68) | DRD3KCNH2DRD2CYP1A2CYP2C19 | |
| SCHEMBL3545896 | 0.88 | DRD3 (0.63) | DRD3KCNH2DRD2CYP1A2CYP2C19 | |
| SCHEMBL13312911 | 0.88 | DRD3 (0.57) | DRD3KCNH2DRD2CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL3550781 | 0.88 | DRD3 (0.62) | DRD3KCNH2DRD2CYP1A2CYP2C19 | |
| SCHEMBL2822280 | 0.85 | DRD3 (0.61) | DRD3KCNH2DRD2CYP1A2CYP2C19 | |
| SCHEMBL2818581 | 0.84 | DRD3 (0.66) | DRD3KCNH2DRD2CYP1A2CYP2C19 | |
| SCHEMBL2819170 | 0.84 | DRD3 (0.62) | DRD3KCNH2DRD2CYP1A2CYP2C19 | |
| SCHEMBL2822383 | 0.84 | DRD3 (0.59) | DRD3KCNH2DRD2CYP1A2CYP2C19 | |
| SCHEMBL13312910 | 0.83 | DRD3 (0.58) | DRD3KCNH2DRD2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926723-B1 | AZABICYCLO (3,1,0) HEXAN DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RCEPTORS | GLAXO GROUP LTD (GB) | 2009-05-13 | — | — | EP | claimed |