SCHEMBL3979987

SCHEMBL3979987

COc1cc(C(=O)N2CCCC(CCOS(=O)(=O)c3ccc(C)cc3)(c3ccc(Cl)c(Cl)c3)C2)cc(OC)c1OC

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TACR2 P21452 4/20 0.53
TACR1 P25103 4/20 0.53
HRH1 P35367 2/20 0.53
TACR3 P29371 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3981504 0.94 TACR2 (0.54) TACR2TACR1HRH1TACR3
SCHEMBL3981423 0.93 TACR2 (0.59) TACR2TACR1HRH1TACR3
SCHEMBL3978155 0.91 TACR2 (0.51) TACR2TACR1HRH1TACR3
SCHEMBL6999634 0.90 TACR2 (0.57) TACR2TACR1HRH1TACR3
SCHEMBL9027870 0.88 TACR2 (0.56) TACR2TACR1HRH1TACR3
SCHEMBL3981791 0.87 TACR2 (0.45) TACR2TACR1TACR3
SCHEMBL3983156 0.86 TACR2 (0.52) TACR2TACR1HRH1TACR3
SCHEMBL6999617 0.85 TACR2 (0.63) TACR2TACR1HRH1TACR3
SCHEMBL6995921 0.85 TACR2 (0.63) TACR2TACR1HRH1TACR3
SCHEMBL7000239 0.85 TACR2 (0.63) TACR2TACR1HRH1TACR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070135434-A1 Sulfonyloxy derivatives SANKYO COMPANY, LIMITED (JP) 2007-06-14 US claimed
US-7560549-B2 Sulfonyloxy derivatives SANKYO COMPANY, LIMITED (JP) 2009-07-14 US disclosed
US-20070135434-A1 Sulfonyloxy derivatives SANKYO COMPANY, LIMITED (JP) 2007-06-14 US disclosed
EP-1754701-A1 SULFONYLOXY DERIVATIVES Sankyo Company, Limited (JP) 2007-02-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135434-A1 Sulfonyloxy derivatives TACR1, NPSR1, TACR2 TACR2 3/4885TACR1 1/4885HRH1 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.