Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 17/20 | 0.68 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | VHL | P40337 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980721 | 1.00 | NR1H3 (0.68) | NR1H3NR1H2ALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL3985833 | 0.99 | NR1H3 (0.67) | NR1H3NR1H2ALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL3985826 | 0.99 | NR1H3 (0.67) | NR1H3NR1H2ALDH1A1MAPTMEN1 | |
| SCHEMBL3980302 | 0.87 | NR1H3 (0.76) | NR1H3NR1H2ALDH1A1MAPTMEN1 | |
| SCHEMBL3980308 | 0.87 | NR1H3 (0.76) | NR1H3NR1H2ALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL3982514 | 0.87 | NR1H3 (0.75) | NR1H3NR1H2ALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL3982512 | 0.87 | NR1H3 (0.75) | NR1H3NR1H2ALDH1A1MAPTMEN1 | |
| SCHEMBL3981147 | 0.85 | NR1H3 (0.72) | NR1H3NR1H2ALDH1A1MAPTMEN1 | |
| SCHEMBL3981137 | 0.85 | NR1H3 (0.72) | NR1H3NR1H2ALDH1A1MAPTMEN1 | |
| SCHEMBL3985623 | 0.85 | NR1H3 (0.69) | NR1H3NR1H2ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560586-B2 | Acid and ester compounds and methods of using the same | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-14 | — | — | US | claimed |
| US-20060041164-A1 | Acid and ester compounds and methods of using the same | GLAXOSMITHKLINE LLC | 2006-02-23 | — | — | US | claimed |
| US-7560586-B2 | Acid and ester compounds and methods of using the same | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-14 | — | — | US | disclosed |
| US-7560586-B2 | Acid and ester compounds and methods of using the same | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-14 | — | — | US | disclosed |
| US-7560586-B2 | Acid and ester compounds and methods of using the same | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-14 | — | — | US | disclosed |
| US-20060041164-A1 | Acid and ester compounds and methods of using the same | GLAXOSMITHKLINE LLC | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060041164-A1 | Acid and ester compounds and methods of using the same | NR1H3, NR1H2, PPARA | NR1H3 1/4885NR1H2 2/4885ALDH1A1 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.