⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980312 | 1.00 | — | — | |
| SCHEMBL6264327 | 0.95 | — | — | |
| SCHEMBL337038 | 0.86 | USP2 (0.32) | — | |
| SCHEMBL337733 | 0.86 | USP2 (0.32) | — | |
| SCHEMBL2452716 | 0.86 | USP2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL1027415 | 0.85 | USP2 (0.31) | — | |
| SCHEMBL146253 | 0.85 | — | — | |
| SCHEMBL6700574 | 0.85 | — | — | |
| SCHEMBL146254 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL1026859 | 0.85 | USP2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491718-B2 | Sulfonamides having antiangiogenic and anticancer activity | ABBOTT LABORATORIES (US) | 2009-02-17 | — | — | US | disclosed |
| US-20040167128-A1 | Sulfonamides having antiangiogenic and anticancer activity | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040157836-A1 | Sulfonamides having antiangiogenic and anticancer activity | ABBOTT LABORATORIES | 2004-08-12 | — | — | US | disclosed |