Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 1.00 |
| ▸ | PDE4A | P27815 | 19/20 | 1.00 |
| ▸ | PDE4C | Q08493 | 19/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3170474 | 0.93 | PDE4A (1.00) | PDE4BPDE4APDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL3166585 | 0.92 | PDE4A (0.98) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13526286 | 0.89 | PDE4B (0.80) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3170778 | 0.89 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL3176923 | 0.88 | PDE4B (0.98) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3177117 | 0.87 | PDE4A (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13526462 | 0.87 | PDE4B (0.77) | PDE4BPDE4APDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL3176441 | 0.86 | PDE4A (0.98) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL28664943 | 0.85 | PDE4A (0.84) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3174538 | 0.85 | PDE4A (1.00) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1308440-B1 | PIPERIDINE DERIVATIVES AND DRUGS CONTAINING THESE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2009-05-06 | — | — | EP | claimed |
| US-7649095-B2 | Piperidine derivatives and agent comprising the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-01-19 | — | — | US | disclosed |
| EP-1308440-B1 | PIPERIDINE DERIVATIVES AND DRUGS CONTAINING THESE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2009-05-06 | — | — | EP | disclosed |