SCHEMBL3980533

SCHEMBL3980533

COc1ccc(COc2ccc([C@@H](C)CC(=O)O)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 15/20 0.71
NPC1 O15118 1/20 0.60
POLB P06746 1/20 0.60
RAB9A P51151 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
RXRA P19793 1/20 0.56
RXRB P28702 1/20 0.56
CMKLR1 Q99788 1/20 0.55
PLA2G4B P0C869 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3980530 1.00 FFAR1 (0.71) FFAR1NPC1POLBRAB9ASMN1; SMN2
SCHEMBL8162876 0.88 FFAR1 (0.67) FFAR1CMKLR1
SCHEMBL2207966 0.88 FFAR1 (0.56) FFAR1
SCHEMBL13140284 0.86 FFAR1 (0.62) FFAR1RXRARXRBCMKLR1
SCHEMBL13140178 0.86 FFAR1 (0.62) FFAR1RXRARXRBCMKLR1
SCHEMBL13140346 0.86 FFAR1 (0.68) FFAR1RXRARXRBCMKLR1
SCHEMBL14495983 0.85 FFAR1 (0.58) FFAR1RXRARXRBCMKLR1
SCHEMBL13140338 0.84 FFAR1 (0.70) FFAR1NPC1POLBRAB9ASMN1; SMN2
SCHEMBL13139951 0.84 FFAR1 (0.63) FFAR1CMKLR1
SCHEMBL13140291 0.84 FFAR1 (0.81) FFAR1NPC1POLBRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009055932-A1 SUBSTITUTED PHENYLPROPIONIC ACIDS AS STIMULATORS OF HEMATOPOIESIS AND ERYTHROPOIESIS PROMETIC BIOSCIENCES INC. (CA) 2009-05-07 WO disclosed