⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398103 | 1.00 | — | — | |
| SCHEMBL11369616 | 0.84 | HCAR2 (0.39) | — | |
| SCHEMBL4450112 | 0.83 | — | — | |
| SCHEMBL4450117 | 0.83 | — | — | |
| SCHEMBL690477 | 0.80 | — | — | |
| SCHEMBL19017506 | 0.80 | — | — | |
| SCHEMBL265582 | 0.80 | — | — | |
| SCHEMBL4450088 | 0.79 | — | — | |
| SCHEMBL4450090 | 0.79 | — | — | |
| SCHEMBL11286576 | 0.79 | HCAR2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9809822-B2 | Triptolide derivatives and preparation method and use thereof | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-11-07 | — | — | US | claimed |
| US-9809822-B2 | Triptolide derivatives and preparation method and use thereof | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-11-07 | — | — | US | disclosed |
| US-20160362691-A1 | TRIPTOLIDE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | HONG KONG BAPTIST UNIVERSITY (HK) | 2016-12-15 | — | — | US | disclosed |
| US-8101645-B2 | Thienopyrroles and pyrrolothiazoles as new therapeutic agents | ABBOTT LABORATORIES (US) | 2012-01-24 | — | — | US | disclosed |
| US-8101645-B2 | Thienopyrroles and pyrrolothiazoles as new therapeutic agents | ABBOTT LABORATORIES (US) | 2012-01-24 | — | — | US | disclosed |
| US-8101645-B2 | Thienopyrroles and pyrrolothiazoles as new therapeutic agents | ABBOTT LABORATORIES (US) | 2012-01-24 | — | — | US | disclosed |
| US-20090326019-A1 | 3,4-BICYCLIC PYRROLIDINE ANTIVIRALS | ENANTA PHARMACEUTICALS, INC. | 2009-12-31 | — | — | US | disclosed |
| US-20090209609-A1 | Thienopyrroles and pyrrolothiazoles as new therapeutic agents | ABBVIE INC. | 2009-08-20 | — | — | US | disclosed |
| US-20090209609-A1 | Thienopyrroles and pyrrolothiazoles as new therapeutic agents | ABBVIE INC. | 2009-08-20 | — | — | US | disclosed |
| US-20090209609-A1 | Thienopyrroles and pyrrolothiazoles as new therapeutic agents | ABBVIE INC. | 2009-08-20 | — | — | US | disclosed |
| US-4414017-A | PLANT GROWTH REGULATORS | CHEVRON RESEARCH COMPANY (US) | 1983-11-08 | — | — | US | disclosed |
| US-4368068-A | PRE- AND POSTEMERGENCE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-11 | — | — | US | disclosed |
| EP-0046467-A1 | Quinoxaline derivatives and herbicidal composition | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-03-03 | — | — | EP | disclosed |
| EP-0046468-A1 | Quinoxaline derivatives and herbicidal composition | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-03-03 | — | — | EP | disclosed |
| EP-0042750-A2 | Quinoxalinyloxy ethers as selective weed control agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-12-30 | — | — | EP | disclosed |
| EP-0030867-A1 | Process for the preparation of substituted pyridinyloxy ethers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-24 | — | — | EP | disclosed |
| US-4266063-A | FROM A HALOPYRIDINE AND HYDROQUINONE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| EP-0024907-A1 | Pyridyloxyphenoxycrotonic acid derivatives, their preparation, compositions thereof and their use as selective weed control agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-11 | — | — | EP | disclosed |
| WO-1981000563-A1 | PYRIDINYLOXYPHENOXY LOWER ALKENOIC ACIDS,ESTERS OR AMIDES THEREOF AS SELECTIVE WEED CONTROL AGENTS | DU PONT | 1981-03-05 | — | — | WO | disclosed |
| US-4254262-A | IN THE PRESENCE OF A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |