SCHEMBL3982552

SCHEMBL3982552

CC1(C)C(=O)N(c2ccc(F)c(C(F)(F)F)c2)C(=O)N1Cc1ccccc1Nc1ccc(F)cc1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 10/20 0.59
IGF1R P08069 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1771939 0.94 AR (0.62) ARIGF1R
SCHEMBL3991583 0.94 AR (0.58) ARIGF1R
SCHEMBL1206882 0.91 AR (0.58) AR
SCHEMBL3989684 0.90 AR (0.58) AR
SCHEMBL3987044 0.89 AR (0.53) ARIGF1R
SCHEMBL3532441 0.89 AR (0.56) AR
SCHEMBL3523801 0.88 AR (0.54) ARIGF1R
Hydrochloric Acid SCHEMBL3524778 0.88 AR (0.52) ARIGF1R
Hydrochloric Acid SCHEMBL3524979 0.88 AR (0.53) ARIGF1R
SCHEMBL3528150 0.87 AR (0.56) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2061767-B1 Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use SANOFI SA (FR) 2014-12-17 EP disclosed
EP-2061767-A1 ARYLAMINOARYL-ALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, PROCESSES FOR PREPARING THEM, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THEIR USE Sanofi-Aventis (FR) 2009-05-27 EP disclosed
WO-2008017381-A1 ARYLAMINOARYL-ALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, PROCESSES FOR PREPARING THEM, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THEIR USE SANOFI-AVENTIS (FR) 2008-02-14 WO disclosed