Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 6/20 | 0.38 |
| ▸ | RAF1 | P04049 | 5/20 | 0.38 |
| ▸ | TEK | Q02763 | 4/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39711 | 0.94 | SLC34A2 (0.46) | SLC34A2BRAFRAF1TEKKDR | |
| SCHEMBL46430 | 0.91 | SLC34A2 (0.47) | SLC34A2BRAFRAF1TEKKDR | |
| SCHEMBL46772 | 0.90 | SLC34A2 (0.41) | SLC34A2BRAFRAF1TEKKDR | |
| SCHEMBL46952 | 0.89 | SLC34A2 (0.44) | SLC34A2BRAFRAF1TEKKDR | |
| SCHEMBL46664 | 0.86 | SLC34A2 (0.49) | SLC34A2BRAFRAF1TEKKDR | |
| SCHEMBL39707 | 0.86 | SLC34A2 (0.58) | SLC34A2BRAFRAF1TEKKDR | |
| SCHEMBL39960 | 0.86 | CYP1A2 (0.40) | SLC34A2SRCMAPTALDH1A1KDM4E | |
| SCHEMBL39971 | 0.85 | SLC34A2 (0.59) | SLC34A2BRAFRAF1TEKNPSR1 | |
| SCHEMBL46629 | 0.85 | SLC34A2 (0.51) | SLC34A2BRAFRAF1TEKLCK | |
| SCHEMBL15444399 | 0.84 | SLC34A2 (0.45) | SLC34A2BRAFRAF1TEKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-A2 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | Ardelyx, Inc. (US) | 2013-05-15 | — | — | EP | disclosed |
| EP-2591354-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | Ardelyx, Inc. (US) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012054110-A2 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |