SCHEMBL3982817 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	SERPINE1	P05121	6/20	0.57

▸	PTPN1	P18031	3/20	0.48

▸	PTPN2	P17706	1/20	0.48

▸	PTPN11	Q06124	1/20	0.48

▸	ESR1	P03372	2/20	0.40

▸	PRKCA	P17252	1/20	0.40

▸	AKR1C4	P17516	1/20	0.38

▸	AKR1C3	P42330	1/20	0.38

▸	AKR1C2	P52895	1/20	0.38

▸	AKR1C1	Q04828	1/20	0.38

▸	TYR	P14679	1/20	0.37

▸	L3MBTL1	Q9Y468	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28219841	1.00	SERPINE1 (0.57)	SERPINE1PTPN1PTPN2PTPN11ESR1
SCHEMBL15303745	0.91	SERPINE1 (0.58)	SERPINE1PTPN1PTPN2PTPN11ESR1
SCHEMBL28456939	0.89	SERPINE1 (0.56)	SERPINE1PTPN1PTPN2PTPN11ESR1
SCHEMBL17156389	0.87	SERPINE1 (0.46)	SERPINE1PTPN1PTPN2PTPN11ESR1
SCHEMBL28178896	0.87	SERPINE1 (0.46)	SERPINE1PTPN1PTPN2PTPN11ESR1
SCHEMBL20578289	0.87	SERPINE1 (0.55)	SERPINE1PTPN1PTPN2PTPN11ESR1
SCHEMBL3228891	0.87	SERPINE1 (0.55)	SERPINE1PTPN1PTPN2PTPN11ESR1
SCHEMBL6763222	0.84	SERPINE1 (0.56)	SERPINE1PTPN1PTPN2PTPN11ESR1
SCHEMBL20530411	0.82	SERPINE1 (0.57)	SERPINE1PTPN1PTPN2PTPN11ESR1
SCHEMBL28064168	0.82	SERPINE1 (0.57)	SERPINE1PTPN1PTPN2PTPN11ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009060304-A2	EMBLICA OFFICINALIS PLANT EXTRACTS AND USES THEREOF	AVESTHAGEN LIMITED (IN)	2009-05-14	—	—	WO	disclosed